| Arsenic trioxide |
Influence on cell proliferation in tumor tissue |
Tumor volume |
2.00 mg/kg |
AGS (xenograft0 |
Mus musculus |
BALB/c athymin nude mice |
|
|
| Arsenic trioxide |
Influence on cell proliferation in tumor tissue |
Body weight |
2.00 mg/kg |
AGS (xenograft0 |
Mus musculus |
BALB/c athymin nude mice |
|
|
| Arsenic trioxide |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
2.00 mg/kg |
AGS (xenograft0 |
Mus musculus |
BALB/c athymin nude mice |
|
|
| Arsenic trioxide |
Influence on cell viability in presence of ruxolitinib |
MTT Assay |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell viability in presence of ruxolitinib |
MTT Assay |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell motility in presence of ruxolitinib |
Colony formation assay |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell motility in presence of ruxolitinib |
Colony formation assay |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell cycle in presence of ruxolitinib |
Flow cytometry |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell cycle in presence of ruxolitinib |
Flow cytometry |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell apoptosis in presence of ruxolitninib |
Flow cytometry- annexin V binding and propidium iodide staining |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell apoptosis in presence of ruxolitninib |
Flow cytometry- annexin V binding and propidium iodide staining |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell apoptosis in presence of ruxolitninib |
Immunofluorescence |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on cell apoptosis in presence of ruxolitninib |
Immunofluorescence |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on apoptotic mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on ROS associated mRNA expression level in presence of ruxolitninib |
RT-qPCR |
2.00 µM |
U937 |
Homo sapiens |
|
|
|
| Arsenic trioxide |
Influence on protein activity |
Western Blot |
2.00 µM |
KG-1 |
Homo sapiens |
|
|
|
